Azelastine CAS NO.58581-89-8

Identification Azelastine hydrochloride occurs as a white, almost odorless, crystalline powder with a bitter taste. It is sparingly soluble in water…

Identification Azelastine hydrochloride occurs as a white, almost odorless, crystalline powder with a bitter taste. It is sparingly soluble in water, methanol, and propylene glycol and slightly soluble in ethanol, octanol, and glycerine. Use and Background Azelastine is an anti-histamine, a chemical that blocks the effects of histamine, another chemical that is responsible for some of the symptoms in allergic reactions. Azelastine is chemically different from other anti-histamines and is used only as a nasal inhaler for the treatment of symptoms of seasonal allergic rhinitis, such as runny nose, sneezing and nasal itching. Route Azelastine hydrochloride is synthesized from P-Chlorophenylacetic acid Phthalic anhydride and 1-Methylazepan-4-ol.